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KMID : 0378020060490090036
New Medical Journal
2006 Volume.49 No. 9 p.36 ~ p.42
Clinical Value of Magnetic Resonance Angiography for Screening of Unruptured Aneurysm
Jung Sung-Sam

Abstract
Objectives: The aim of this study is to evaluate the role of magnetic resonance angiography (MRA) in screening of unruptured aneurysm and to examine the relationship between unruptured aneurysm detected on MRA and vascular risk factors.

Method: We retrospectively assessed 212 patients who visited our institution and underwent both brain magnetic resonance imaging (MRI) and three-dimensional, time-of-flight MRA of the head. We evaluated unruptured aneurysm of the intracranial arteries using MRA. Age, sex, history of hypertension, history of ischemic heart disease, family history of cerebrovascular disease, HbA1c, total cholesterol, fasting triglyceride, high density lipoprotein, low density lipoprotein, hematocrit, smoking and left ventricular hypertrophy (LVH) on ECG were included in the analysis.

Results: Unruptured aneurysms were found in 10 patients (4.7%) and conventional angiography confirmed the 9 aneurysms among them. Multiple logistic regression analysis showed that significant and independent predictors for unruptured aneurysm of the intracranial arteries were female sex and hypertension.

Conclusion: The present study suggested that unruptured aneurysm detected in MRA was related to hypertension and female sex. MRA is clinically useful method for screening unruptured aneurysm in patients with risk factors and selecting high-yield patients for conventional angiography
KEYWORD
Magnetic resonance angiography, Risk factor, Unruptured aneurysm
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